| verb | lower someone's spirits; make downhearted “These news depressed her” |
| adjective | marked by low spirits; showing no enthusiasm “a dispirited and divided Party” |
| adjective | filled with melancholy and despondency “gloomy at the thought of what he had to face” |
| depressant | adjective | capable of depressing physiological or psychological activity or response by a chemical agent |
| depressant | noun | a drug that reduces excitability and calms a person |
| dejection | noun | a state of melancholy depression |
| dismay | noun | the feeling of despair in the face of obstacles |
| demoralization | noun | depression resulting from an undermining of your morale |
| demoralisation | noun | depression resulting from an undermining of your morale |
| dispiritedness | noun | a feeling of low spirits |
| listlessness | noun | a feeling of lack of interest or energy |
| gloominess | noun | a feeling of melancholy apprehension |
| downheartedness | noun | a feeling of low spirits |
| lowness | noun | a feeling of low spirits |
| low-spiritedness | noun | a feeling of low spirits |